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Diclofenac Topical Solution ve Trombosit agregasyonu inhibisyonu

Diclofenac Topical Solution ilacının Trombosit agregasyonu inhibisyonu hastalığı ile etkileşiminin güvenlik kontrolünün sonucu.

Kontrolün sonucu:
Diclofenac Topical Solution <> Trombosit agregasyonu inhibisyonu
Güncellik: 23.07.2019 Eleştirmen: MD PHD P.M. Shkutko, in

Drugs.com, Rxlist.com, Webmd.com, Medscape.com gibi yetkili kaynaklara dayalı kontrolün sonucunda bu ilacın bu komorbid hastalık ile etkileşmesi halinde zarar verebilen veya olumsuz etkisini artırabilen kontrendikasyonlar veya yan etkiler bulundu.

Tüketici:

Steroid olmayan anti-inflamatuar ilaçlar (NSAID) geri dönüşümlü trombosit adezyon ve toplama engeller ve bazı hastalarda kanama zamanı uzayabilir. Aspirin dışında, önerilen dozlarda en NSAID görülen trombosit etkileri süresi genellikle hafif ve nispeten kısa ama temel hemostatik anormallikleri olan hastalarda daha belirgin olabilir. Trombositopeni nadiren de NSAID kullanımı sırasında bildirilmiştir. NSAID ile tedavi hastalarda dikkatle anlamlı aktif kanama veya kanama oluşturma, hemofili, K vitamini eksikliği, hypoprothrombinemia, trombositopeni, thrombocytopathy olduğunu, ya da şiddetli karaciğer yetmezliği ile ilişkili hemostatik ve/veya pıhtılaşma kusurları da dahil olmak üzere uygulanmalıdır. Seçici siklooksijenaz engelleyen-2 (örneğin, COX-2 inhibitörleri) NSAİ ilaçlar belirtilen dozlarda kanama zamanı trombosit fonksiyon bozukluğu ya da görünmez ve kanama riskini önemli ise tercih edilebilir.

Kaynaklar
  • Berliner S, Sidi Y, Shaklai M, Pinkhas J "Appearance of thrombocytopenia and benign monoclonal gammopathy following intake of drugs." Acta Haematol 67 (1982): 71-2
  • Leese PT, Hubbard RC, Karim A, Isakson PC, Yu SS, Geis GS "Effects of celecoxib, a novel cyclooxygenase-2 inhibitor, on platelet function in healthy adults: A randomized, controlled trial." J Clin Pharmacol 40 (2000): 124-32
  • Thwaites BK, Nigus DB, Bouska GW, Mongan PD, Ayala EF, Merrill GA "Intravenous ketorolac tromethamine worsens platelet function during knee arthroscopy under spinal anesthesia." Anesth Analg 82 (1996): 1176-81
  • Bernhard GC "Worldwide safety experience with nabumetone." J Rheumatol 19 (1992): 48-57
  • Katz ME, Wang P "Fenoprofen-associated thrombocytopenia." Ann Intern Med 92 (1980): 262
  • Gerber D "Adverse reactions of piroxicam." Drug Intell Clin Pharm 21 (1987): 707-10
  • Robb PJ, Rollin AM, Saunders DA "Diclofenac and post-tonsillectomy haemorrhage." Clin Otolaryngol 20 (1995): 483
  • "Product Information. Daypro (oxaprozin)." Searle, Skokie, IL.
  • Green D, Davies RO, Holmes GI et al "Effects of diflunisal on platelet function and fecal blood loss." Pharmacotherapy 3 (1983): s65-9
  • Baber N, Halliday LDC, van den Heuval, et al "Indomethacin in rheumatoid arthritis: clinical effects, pharmacokinetics, and platelet studies in responders and non-responders." Ann Rheum Dis 38 (1979): 128-37
  • O'Brien WM "Long-term efficacy and safety of tolmetin sodium in treatment of geriatric patients with rheumatoid arthritis and osteoarthritis: a retrospective study." J Clin Pharmacol 23 (1983): 309-23
  • Rosenbaum JT, O'Connor M "Thrombocytopenia associated with sulindac." Arthritis Rheum 24 (1981): 753-4
  • Buchanan GR, Martin V, Levine PH, et al "The effects of "anti-platelet" drugs on bleeding time and platelet aggregation in normal human subjects." Am J Clin Pathol 68 (1977): 355-9
  • "Product Information. Celebrex (celecoxib)." Searle, Chicago, IL.
  • Camba L, Joyner MV "Acute thrombocytopenia following ingestion of indomethacin." Acta Haematol 71 (1984): 350-2
  • Catalano MA "Worldwide safety experience with diclofenac." Am J Med 80 (1986): 81-7
  • "Product Information. Indocin (indomethacin)." Merck & Co, Inc, West Point, PA.
  • "Product Information. Lodine (etodolac)." Wyeth-Ayerst Laboratories, Philadelphia, PA.
  • Bobrove AM "Diflunisal-associated thrombocytopenia in a patient with rheumatoid arthritis ." Arthritis Rheum 31 (1988): 148-9
  • Bjornstad H, Vik O "Thrombocytopenic purpura associated with piroxicam." Br J Clin Pract 40 (1986): 42
  • "Product Information. Naprosyn (naproxen)." Syntex Laboratories Inc, Palo Alto, CA.
  • Schattenkirchner M "An updated safety profile of etodolac in several thousand patients." Eur J Rheumatol Inflamm 10 (1990): 56-65
  • Longenecker GL, Swift IA, Bowen RJ, et al "Kinetics of ibuprofen effect on platelet and endothelial prostanoid release." Clin Pharmacol Ther 37 (1985): 343-8
  • "Product Information. Ansaid (flurbiprofen)." Pharmacia and Upjohn, Kalamazoo, MI.
  • "Product Information. Clinoril (sulindac)." Merck & Co, Inc, West Point, PA.
  • Sanz MA, Martinez JA, Gomis F, Garcia-Borras JJ "Sulindac-induced bone marrow toxicity." Lancet 2 (1980): 802-3
  • "Product Information. Orudis (ketoprofen)." Wyeth-Ayerst Laboratories, Philadelphia, PA.
  • Epstein M, Vickars L, Stein H "Diclofenac induced immune thrombocytopenia." J Rheumatol 17 (1990): 1403-4
  • Bondeson J, Berglund S "Diclofenac-induced thrombocytopenic purpura with renal and hepatic involvement." J Intern Med 230 (1991): 543-7
  • Price AJ, Obeid D "Spontaneous non-gastrointestinal bleeding associated with diclofenac ." Lancet 2 (1989): 1520
  • Hirsh J, Dalen JE, Fuster V, Harker LB, Patrono C, Roth G "Aspirin and other platelet-active drugs: the relationship among dose, effectiveness, and side effects." Chest 108 Suppl (1995): s247-57
  • Kramer MR, Levene C, Hershko C "Severe reversible autoimmune haemolytic anaemia and thrombocytopenia associated with diclofenac therapy." Scand J Haematol 36 (1986): 118-20
  • Tomson G, Lunell N-O, Oliw E, Rane A "Relation of naproxen kinetics to effect on platelet prostaglandin release in men and dysmenorrheic women." Clin Pharmacol Ther 29 (1981): 168-73
  • Shojania AM, Rusen SD "Thrombocytopenia secondary to sulindac therapy." Can Med Assoc J 125 (1981): 1313
  • "Product Information. Relafen (nabumetone)." SmithKline Beecham, Philadelphia, PA.
  • "Product Information. Vioxx (rofecoxib)." Merck & Co, Inc, West Point, PA.
  • Gandini R, Cunietti E, Pappalepore V, et al "Effects of intravenous high doses of ketoprofen on blood clotting, bleeding time and platelet aggregation in man." J Int Med Res 11 (1983): 243
  • Park GD, Spector R, Headstream T, Goldberg M "Serious adverse reactions associated with sulindac." Arch Intern Med 142 (1982): 1292-4
  • Hyson CP, Kazakoff MA "A severe multisystem reaction to sulindac." Arch Intern Med 151 (1991): 387-8
  • Brooks CD, Linet OI, Schellenberg D, Turner LF, Defesche CL, Teoh KW, Johnson JH, Assenzo JR "Clinical safety of flurbiprofen." J Clin Pharmacol 30 (1990): 342-51
  • "Product Information. Dolobid (diflunisal)." Merck & Co, Inc, West Point, PA.
  • "Product Information. Tolectin (tolmetin)." McNeil Pharmaceutical, Raritan, NJ.
  • Concannon MJ, Meng L, Welsh CF, Puckett CL "Inhibition of perioperative platelet aggregation using toradol (ketorolac)." Ann Plast Surg 30 (1993): 264-6
  • "Product Information. Nalfon (fenoprofen)." Xspire Pharma, Ridgeland, MS.
  • Karachalios GN, Parigorakis JG "Thrombocytopenia and sulindac." Ann Intern Med 104 (1986): 128
  • Jick H, Derby LE, Garcia Rodriguez LA, Jick SS, Dean AD "Nonsteroidal antiinflammatory drugs and certain rare, serious adverse events: a cohort study." Pharmacotherapy 13 (1993): 212-7
  • Stambaugh JE Jr, Gordon RL, Geller R "Leukopenia and thrombocytopenia secondary to clinoril therapy." Lancet 2 (1980): 594
  • "Product Information. Voltaren (diclofenac)." Novartis Pharmaceuticals, East Hanover, NJ.
  • Robinson PM, Ahmed I "Diclofenac and post-tonsillectomy haemorrhage." Clin Otolaryngol 19 (1994): 344-5
  • Kim HL, Kovacs MJ "Diclofenac-associated thrombocytopenia and neutropenia." Ann Pharmacother 29 (1995): 713-5
  • "Product Information. Mobic (meloxicam)" Boehringer-Ingelheim, Ridgefield, CT.
  • Khazan U, Toth M, Mutgi A "Diclofenac sodium and bruising ." Ann Intern Med 112 (1990): 472-3
  • Schafer AI "Effects of nonsteroidal antiinflammatory drugs on platelet function and systemic hemostasis." J Clin Pharmacol 35 (1995): 209-19
  • "Product Information. Motrin (ibuprofen)." Pharmacia and Upjohn, Kalamazoo, MI.
  • "Product Information. Feldene (piroxicam)." Pfizer US Pharmaceuticals, New York, NY.
  • Poldre PA "Naproxen thrombocytopenia." Am J Hematol 31 (1989): 74
Diclofenac Topical Solution

Jenerik adı: diclofenac topical

Marka adı: DST Plus Pak, Pennsaid, Solaraze, Voltaren Topical, Diclozor, Voltaren, Flector Patch, Klofensaid II, Vopac MDS, Xrylix, Flector, Licart

Eşdeğer ilaçlar: Diclofenac topical, Diclofenac (Topical)

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