Bismuth Subcitrate, Metronidazole, and Tetracycline ve Karaciğer hastalığı
Bismuth Subcitrate, Metronidazole, and Tetracycline ilacının Karaciğer hastalığı hastalığı ile etkileşiminin güvenlik kontrolünün sonucu.
Drugs.com, Rxlist.com, Webmd.com, Medscape.com gibi yetkili kaynaklara dayalı kontrolün sonucunda bu ilacın bu komorbid hastalık ile etkileşmesi halinde zarar verebilen veya olumsuz etkisini artırabilen kontrendikasyonlar veya yan etkiler bulundu.
Tüketici:Metronidazol yoğun hem de farmakolojik olarak etkin ve etkin olmayan bileşikler karaciğer tarafından metabolize edilir. Metronidazol plazma klerensi böbrek fonksiyonu bozulmuş olan hastalarda uzun süreli azalmış ve Yarılanma Ömrü olabilir. Metronidazol ile tedavi dikkatle ve azaltılmış dozlarda ciddi karaciğer hastalığı olan hastalarda uygulanmalıdır.
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- Loft S, Sonne J, Dossing M, Andreasen PB "Metronidazole pharmacokinetics in patients with hepatic encephalopathy." Scand J Gastroenterol 22 (1987): 117-23
- Jensen JC, Gugler R "Single- and multiple-dose metronidazole kinetics." Clin Pharmacol Ther 34 (1983): 481-7
- Lau AH, Evans R, Chang CW, Seligsohn R "Pharmacokinetics of metronidazole in patients with alcoholic liver disease." Antimicrob Agents Chemother 31 (1987): 1662-4
- Farrell G, Baird-Lambert J, Cvejic M, Buchanan N "Disposition and metabolism of metronidazole in patients with liver failure." Hepatology 4 (1984): 772-6
Jenerik adı: bismuth subcitrate potassium / metronidazole / tetracycline
Marka adı: Pylera
Eşdeğer ilaçlar: Bismuth subcitrate potassium, metronidazole, and tetracycline
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