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Azathioprine Intravenous ve Böbrek yetmezliği

Azathioprine Intravenous ilacının Böbrek yetmezliği hastalığı ile etkileşiminin güvenlik kontrolünün sonucu.

Kontrolün sonucu:

Azathioprine Intravenous <> Böbrek yetmezliği

Güncellik: 23.07.2019 Eleştirmen: MD PHD P.M. Shkutko, in

Drugs.com, Rxlist.com, Webmd.com, Medscape.com gibi yetkili kaynaklara dayalı kontrolün sonucunda bu ilacın bu komorbid hastalık ile etkileşmesi halinde zarar verebilen veya olumsuz etkisini artırabilen kontrendikasyonlar veya yan etkiler bulundu.

Tüketici:

Azatioprin böbrek yetmezliği olan hastalarda birikebilir. Azatioprin ile tedavi dikkatli uygulanmalıdır ve böbrek yetmezliği olan hastalarda doz azaltılması gerekebilir.

Kaynaklar

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McHenry PM, Allan JG, Rodger RS, Lever RS "Nephrotoxicity due to azathioprine." Br J Dermatol 128 (1993): 106
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Chan GL, Erdmann GR, Gruber SA, et al "Pharmacokinetics of 6-thiouric acid and 6-mercaptopurine in renal allograft recipients after oral administration of azathioprine." Eur J Clin Pharmacol 36 (1989): 265-71
Duttera MJ, Carolla RL, Gallelli JF, et al "Hematuria and crystalluria after high-dose 6-mercaptopurine administration." N Engl J Med 287 (1972): 292-4