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Isoniazid, pyrazinamide, and rifampin ve Kolit

Isoniazid, pyrazinamide, and rifampin ilacının Kolit hastalığı ile etkileşiminin güvenlik kontrolünün sonucu.

Kontrolün sonucu:

Isoniazid, pyrazinamide, and rifampin <> Kolit

Güncellik: 23.07.2019 Eleştirmen: MD PHD P.M. Shkutko, in

Drugs.com, Rxlist.com, Webmd.com, Medscape.com gibi yetkili kaynaklara dayalı kontrolün sonucunda bu ilacın bu komorbid hastalık ile etkileşmesi halinde zarar verebilen veya olumsuz etkisini artırabilen kontrendikasyonlar veya yan etkiler bulundu.

Tüketici:

Psödomembranöz kolit en antibakteriyel ilaçlarla bildirilmiştir ve şiddeti hafiften yaşamı için aralığı tehdit eden, tedavi kesildikten sonra aşağıdaki iki aya varan bir başlangıç ile. Antibiyotik tedavisi toksinin antibiyotiğe bağlı kolit birincil nedeni olduğuna inanılan olan Clostridium difficile, kolon ve izin büyümesi normal flora değiştirebilir. Kolit genellikle şiddetli ve kalıcı ishal ve şiddetli karın krampları ile karakterize, ve kan ve mukus geçişi ile ilişkili olabilir. En yaygın suçluları klindamisin, ampisilin, amoksisilin, ampisilin) bu oranda ve sarılık vardır. Önemli bir antibakteriyel aktiviteye sahip geniş spektrumlu antibiyotik ve diğer ajanlar ile tedavi hastalarda dikkatle gastrointestinal hastalığı öyküsü olan idare, özellikle kolit olmalıdır. Psödomembranöz kolit, eğer ortaya çıkarsa, bu hastalarda daha ağır bir seyir olabilir ve altta yatan hastalık aktivite patlamaları ile ilişkili olabilir dair bazı kanıtlar vardır. (S) soruna neden olan bir antibiyotik eğer ciddi ishal tedavisi sırasında meydana gelirse kesilmelidir. Clostridium difficile ve C. difficile toksini için dışkı testi için dışkı kültürleri tanısal olarak yararlı olabilir. Büyük bir bağırsak endoskopi ağır ishal vakalarında kesin bir tanı için kabul edilebilir.

Kaynaklar

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